If you have any questions regarding diagnosis or management, please refer to the NMOSD service. If the test is positive, please refer the patient into one of the NMOSD centres. If another obvious and definite diagnosis is present.Unexplained ‘encephalitis’ and seizures with brain lesions.‘Atypical MS’ or other uncharacterized CNS demyelination.Recurrent, bilateral or severe optic neuritis Longitudinal or recurrent transverse myelitis.azathioprine) may need to be used much like we treat AQP4 antibody associated NMOSD. If a relapse occurs then additional immunosuppressants (e.g. CDT Unique neurologic symptoms lead to surprising cancer diagnosis April. Since we are not sure about the natural course of the disease, treatment usually consists of a slow taper of corticosteroids (prednisolone) over 6 months to a year after the first event. MOG antibody-associated disorder, Paraneoplastic encephalitis. optic neuritis) and MOG antibodies often have a ‘one-off’ event and usually recover well from their illness Treatment of MOG antibody associated disease In contrast to typical NMOSD (caused by AQP4 antibodies) up to half of the persons with an episode of demyelination (e.g. MOG antibodies are found on the myelin sheath rather than the astrocyte as in AQP4 antibodies and cause damage to the myelin.
However, their discovery is recent and there is much to be learned. MOG antibodies have been reported in some people who have transverse myelitis and/or optic neuritis and/or ADEM (acute disseminated encephalomyelitis) and AQP4 antibody negative NMOSD. MOG stands for Myelin Oligodendrocyte Glycoprotein. MOG antibodies MOG antibody-associated demyelination and NMOSD
0 kommentar(er)
